Open AccessAnthelmintic potential of various extracts of the rhizomes of Curcuma amada Roxb.
Author(s) -
Maharudra S. Rakh,
Rajendra V. Pawar,
Amol Khedkar
Publication year - 2014
Publication title -
asian pacific journal of tropical disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.208
H-Index - 33
ISSN - 2222-1808
DOI - 10.1016/s2222-1808(14)60455-2
Subject(s) - anthelmintic , rhizome , traditional medicine , albendazole , chemistry , ethyl acetate , curcuma , zingiberaceae , biology , chromatography , medicine , ecology
Objective: To investigate the anthelmintic potential of various extracts of the rhizomes of\udCurcuma amada Roxb.\udMethods: Cyclohexane, ethyl acetate, methanol and aqueous extracts of Curcuma amada Roxb.\udagainst Pheretima posthuma, an Indian species of earthworm. Various concentrations (25, 50\udand 100 mg/mL) of these extract were evaluated for anthelmintic activity by recording the time\udrequired for paralysis and death of worms. Albendazole was used as a reference standard drug.\udResults: Methanol and aqueous extracts shows most significant anthelmintic activity compared\udwith standard drug.\udConclusions: Since methanol and aqueous extracts were tested by different chemical tests.\udIt shows presence of carbohydrates, steroid, alkaloids, glycosides and flavanoids. These\udphytoconstituents may be responsible for the said activities