Open AccessIn vitro anthelmintic efficacy of Borassus flabellifer Linn. (Palmae) against Pheretima posthuma
Author(s) -
Prasad G. Jamkhande,
Vikas Annarao Suryawanshi,
Amruta S. Wattamwar,
Sonal Ramrao Barde
Publication year - 2014
Publication title -
asian pacific journal of tropical disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.208
H-Index - 33
ISSN - 2222-1808
DOI - 10.1016/s2222-1808(14)60439-4
Subject(s) - albendazole , anthelmintic , traditional medicine , saline , biology , medicine , veterinary medicine , surgery
Objective: To investigate the anthelmintic activity of Borassus flabellifer (B. flabellifer) Linn.\udleaves against Indian adult earth worms (Pheretima posthuma).\udMethods: The B. flabellifer leaves and Indian adult earth worms (Pheretima posthuma) were\udcollected and authenticated. Earth worms were grouped and treated with extract at 10, 20 and 50\udmg/mL concentration, albendazole (10 mg/mL) as a standard and normal saline. The paralysis time\udand mortality time was considered as indicator of anthelmintic efficacy.\udResults: All the extracts showed concentration dependent activity but significant activity was\udobserved at 50 mg/mL. At concentration 50 mg/mL extract pertained better activity with paralysis\udtime (13.3 min) and death times (17.92 min) when compared to standard albendazole.\udConclusions: The study findings reveal that the methanolic extract of B. flabellifer leaves has\udeffective anthelmintic activity against Indian adult earth worms