Open AccessSero-prevalence and factors associated with Helicobacter pylori infection in Eastern Sudan
Author(s) -
Tajeldin Mohammedien Abdallah,
Hashim Balla Mohammed,
Mamoon Hassan Mohammed,
Abdel Aziem Abdalla Ali
Publication year - 2014
Publication title -
asian pacific journal of tropical disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.208
H-Index - 33
ISSN - 2222-1808
DOI - 10.1016/s2222-1808(14)60326-1
Subject(s) - helicobacter pylori , seroprevalence , medicine , helicobacter pylori infection , logistic regression , gastroenterology , cross sectional study , immunology , serology , antibody , pathology
Objective: To investigate the prevalence of Helicobacter pylori (H. pylori) among patients with\uddyspepsia and to evaluate the correlation between H. pylori infection and socio-demographic\udfactors.\udMethods: This cross-sectional hospital-based study, which ran from June to August 2012,\uddetermined seroprevalence of H. pylori among adult patients in Eastern Sudan. The presence of H.\udpylori was determined using ELISA.\udResults: A total of 225 adult Sudanese patients were enrolled in the study. Of these, 148 (65.8%)\udtested positive for H. pylori. In logistic regression analysis, rural residency (OR=3.933, CI=1.337-\ud11.26, P=0.01) was the only socio-demographic factor that was associated with H. pylori infection.\udThe most common symptoms among seropositive patients were heartburn (OR=30.442, CI=9.478-\ud97.776, P≤0.001) and/or epigastria pain (OR=28.225, CI=4.365-182.508, P≤0.001).\udConclusions: Clinical suspicion can facilitate the detection of H. pylori among patients with\uddyspeptic symptoms in a geographic area with high prevalence of H. pylori infection