Open AccessCarrier state of Haemophilus influenzae type b (Hib), Streptococcus pneumoniae, Streptococcus pyogenes, Neisseria meningitidis and Corynebacterium diphtheriae among school children in Pokhara, Nepal
Author(s) -
Dharm Raj Bhatta,
Shishir Gokhale,
A Sharma,
Umesh Datta Gupta,
Abhishek Gaur,
Supram Gowda,
Shristi Raut,
Sangeeta Thapa,
Rupendra Khadka
Publication year - 2014
Publication title -
asian pacific journal of tropical disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.208
H-Index - 33
ISSN - 2222-1808
DOI - 10.1016/s2222-1808(14)60312-1
Subject(s) - microbiology and biotechnology , corynebacterium diphtheriae , streptococcus pneumoniae , haemophilus influenzae , neisseria meningitidis , streptococcus pyogenes , staphylococcus aureus , biology , diphtheria , vaccination , virology , antibiotics , bacteria , genetics
Objective: To determine the incidence of carrier state of Haemophilus influenzae type b,\udStreptococcus pneumoniae (S. pneumoniae), Streptococcus pyogenes, Neisseria meningitidis and\udCorynebacterium diphtheriae among school children.\udMethods: Specimen from posterior pharyngeal wall and tonsils were collected on calcium\udalginate coated swabs from 1 02 participants. Processing of specimen and antimicrobial\udsusceptibility testing was done by standard procedures.\udResults: Potential pathogens isolated in our study were S. pneumoniae (14.7%), Staphylococcus\udaureus (12.7%), Corynebacterium diphtheriae (3.9%), Streptococcus pyogenes (3.9%) and Haemophilus\udinfluenzae (1.9%). Important findings in antibiogram include high resistance of S. pneumoniae to\udpenicillin (73%) and resistance of Staphylococcus aureus to oxacillin (23%).\udConclusions: Pharyngeal colonization by S. pneumoniae among school children was found high\udand there is need of introduction of pneumococcal vaccines among children. Despite expected\uduniversal vaccination, pharyngeal colonization by Corynebacterium diphtheriae is possible and\udthere is possibility of transmission