Open AccessSocio demographic wise risk assessment of thyroid function abnormalities in far western region of Nepal: A hospital based descriptive study
Author(s) -
Neelu Yadav,
C. Thanpari,
Mukesh Kumar Shrewastwa,
Brijesh Sathian,
Rabindra Kumar Mittal
Publication year - 2013
Publication title -
asian pacific journal of tropical disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.208
H-Index - 33
ISSN - 2222-1808
DOI - 10.1016/s2222-1808(13)60060-2
Subject(s) - subclinical infection , medicine , thyroid , thyroid function , pediatrics , population , thyroid function tests , environmental health
Objective: To know the status of thyroid disorder in population of far western region of Nepal.\udMethods: A total of 808 cases (1 33 men and 675 non pregnant women) were included and\udstudy was carried out using data retrieved from the register maintained in the Department of\udBiochemistry of the Nepalgunj Teaching Hospital between 1st January, 2011 and 28th February,\ud2012. The variables collected were age, sex, and thyroid function profile including free T3, free\udT4 and TSH. Results: The percentage of thyroid disorders was 33.66% in far western region of\udNepal. The people were highly affected by overt hyperthyroidism (14.9%) followed by subclinical\udhyperthyroidism (9.9%). The subclinical hypothyroidism was 7.9% while 1% overt hypothyroidism\udonly in a far western region of Nepal. Females were highly affected by overt hyperthyroidism\ud(17.8%), followed by subclinical hyperthyroidism (11.9%). A total of 5.9% females were affected by\udsubclinical hypothyroidism while only 1.2% by overt hypothyroidism. Males were affected only by\udsubclinical hypothyroidism (18.0%) in this present study. High number of total thyroid dysfunction\udwas observed in 21 to 40 years of age groups, followed by 41 to 60 years of age groups. Less than 40\udyears people were having 1.03, 0.99, 2.51 and 1.15 times risk of developing overt hyperthyroidism,\udsubclinical hyperthyroidism, overt hypothyroidism and subclinical hyperthyroidism respectively\udcompared to greater than 40. Female were having 0.29 times risk of developing subclinical\udhyperthyroidism compared to male. But overt hyperthyroidism, subclinical hyperthyroidism\udand overt hypothyroidism female were having more risk of developing compared to male.\udConclusions: The thyroid disorder, especially overt hyperthyroidism (14.9%) and subclinical\udhyperthyroidism (9.9%) was high. Further studies are required to characterize the reasons for this\udhigh prevalence