Open AccessAntimicrobial activity of Acanthus ilicifolius: Skin infection pathogens
Author(s) -
C. Govindasamy,
M. Arulpriya
Publication year - 2013
Publication title -
asian pacific journal of tropical disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.208
H-Index - 33
ISSN - 2222-1808
DOI - 10.1016/s2222-1808(13)60036-5
Subject(s) - phytochemical , antimicrobial , microbiology and biotechnology , candida albicans , minimum inhibitory concentration , chemistry , glycoside , minimum bactericidal concentration , terpenoid , staphylococcus aureus , traditional medicine , microsporum gypseum , petroleum ether , biology , trichophyton , bacteria , biochemistry , chromatography , medicine , antifungal , genetics , organic chemistry , extraction (chemistry)
Objective: To investigate the antimicrobial activity of Acanthus ilicifolius against the skin\udinfecting bacterial and fungal pathogens. Through the literature survey, the mangrove plant\udAcanthus ilicifolius was used in skin infection diseases and have potential anti-inflammatory\udactivity. Methods: Antimicrobial activity of the leaf extracts was tested using agar well diffusion\udmethod. Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC)\udwere carried out. Results: Among the different extracts, chloroform extract showed maximum\udactivity against the bacterial pathogens methicillin-resistant Staphylococcus aureus, Streptococcus\udpyogenes, Pseudomonas aeruginosa, Candida albicans and Trichophyton rubrum. Methanol and\udacetone extracts showed maximum activity against Staphylococcus epidermis and Lactobacillus\udplantarum respectively. Chloroform extracts showed the lowest MIC (0.5 mg/mL) and MBC (2 mg/\udmL) values against the skin pathogens compared with other extracts. Phytochemical screening\udrevealed the presence of resins, steroids, tannins, glycosides, sugars, carbohydrates, saponins,\udsterols, terpenoids, phenol, alkaloids, cardiac glycosides and catechol. Conclusions: Further,\udthe separation of potential compounds from the crude extracts will be useful for control the skin\udinfection pathogens