Open AccessLarvicidal activity of Andrographis paniculata (Burm.f) Nees against Culex quinquefasciatus Say (Insecta: Diptera-Culicidae), a filarial vector
Author(s) -
BD Sheeja,
D Sindhu,
J Ebanasar,
Solomon Jeeva
Publication year - 2012
Publication title -
asian pacific journal of tropical disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.208
H-Index - 33
ISSN - 2222-1808
DOI - 10.1016/s2222-1808(12)60224-2
Subject(s) - culex quinquefasciatus , andrographis paniculata , instar , biology , larva , toxicology , traditional medicine , bioassay , filariasis , culex , botany , veterinary medicine , medicine , zoology , aedes aegypti , ecology , alternative medicine , pathology , helminths
Objective: The purpose of the present study was to assess the acetone and ethanol extracts\udof Andrographis paniculata against the filarial vector Culex quinquefasciatus. Methods: The\udethanol and acetone extracts of plant leaves was used at 25, 50, 100, 200 and 300 ppm dilution in\udbioassays against second instar larvae of Culex quinquefasciatus. Ten larvae were exposed to the\udleaf extract at different concentration in a final volume of 100 mL formulation taken in 500 mL\udof glass bowl. For avoiding error triplicates were maintained. Tap water was taken as control.\udThe larval mortality at different concentrations and in control was recorded 24 hour continuous\udexposure. Results: The toxicity of ethanol extract of Andrographis paniculata on survival of\udCulex quinquefasciatus reveals that the mortality is dependent on the dose of the plant extract\udand also on time of exposure. Highest mortality rate of 20% and 73.3% was recorded in 300 ppm at\ud3 and 24 h respectively. The similar trend was observed in case of the toxicity of acetone extract.\udConclusions: The results of the present study suggest that the leaf extracts of Andrographis\udpaniculata may have the potential to be used as an ideal eco-friendly approach for the control of\udthe filarial vector Culex quinquefasciatus