Antimicrobial Activity of 22 Plants Used in Urolithiasis Medicine in Western Algeria

Objective: Our investigation is about the determination of the antibacterial efficiency of 22\udmedicinal plants on the four most frequent bacteria in urinary infections. These infections are\udresponsible for more than 15% of urinary stones formation. Methods: We have initiated an\udextraction liquid/solid. In this respect, we have used water extractions according to the standard\udmethods utilized by the local population, i.e: (i) the d écoction, (ii) the infusion, (iii) the mac ération\udand (iiii) the percolation. The microorganisms used are Staphylooccus aureus, Escherichia coli,\udProteus mirabilis and Pseudomonas aeruginosa. The strains were isolated from patients having\udurinary infections. The antibiotic disks Kanamicin, Colistin, Amoxicillin, Gentamicin, Ampicillin\udwere applied to the reference bacteria at concentrations of 30 毺 g, 50毺 g, 25毺 g, 10毺 g et 10毺\udg respectively. Results: These studies showed that decoction (d) had the higher effect with 43.3\ud% followed by percolation (p) (28.3%) and maceration (m) (16.7%). Infusion (i) had a limited effect\ud(11.7%). Escherichia coli (E.coli), Proteus mirabilis, Staphylococcus aureus showed an average\udsensitivity of 28% in each case. However, Pseudomonas aeruginosa, a highly pathogenic and\udresistant bacteria showed up to 17.5% of sensitivity. 16.3% of the plant extracts showed a high\udantimicrobial activity. Pseudomonas aeruginosa was highly resistant to Kanamycin, Amoxicillin\udand Ampicillin and at a lower extent to Colistin and Gentamicin. However, it was sensitive to\udsome plant extracts such as Allium sativum, Artemesia compestris(p,m), Citrus aurantium(p),\udCotula cinerea(p), Lavandula officinalis (d) , Globularia alypum (d) , Juniperus phoeniceae (m) ,\udOlea europaea (p), Pistacia lentiscus (m) , Trachyspermum ammi (m), Zygophyllum album (p)\udand Zingiber officinalis (d). Conclusion: The present work shows that most of the studied plants\udare potentially a good source of antimicrobial agents and it proves the importance of such plants\udin urolithiasis medicine and alternative healthcare