Open AccessIn vitro antibacterial activity of Desmodium gangeticum (L.) DG
Author(s) -
Karthikeyan Krishnasamy,
Gandhi Siddhar Selvam,
R. Srinivasan,
C. Honey Chandran,
S. Kulothungan
Publication year - 2012
Publication title -
asian pacific journal of tropical disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.208
H-Index - 33
ISSN - 2222-1808
DOI - 10.1016/s2222-1808(12)60195-9
Subject(s) - chemistry , kanamycin , antibacterial activity , ciprofloxacin , microbiology and biotechnology , traditional medicine , antibiotics , biology , bacteria , biochemistry , medicine , genetics
Objective: To identify the antibacterial activity of Desmodium gangeticum (D. gangeticum).\udMethods: Antibacterial activity of D. gangeticum was tested with various solvents viz., methanol,\udethanol, chloroform and aqueous extract against various bacterial pathogens such as Klebsiella\udpneumoniae, Escherichia coli, Salmonella typhi, Streptococcus mutants and Pseudomonas\udaeruginosa. Antibiotic sensitivity assay was performed with amoxicillin, kanamycin, tetracyclin,\udciprofloxacin and penicillin. Result: Of the selected several extract, the methanolic extract\udshowed maximum zone of inhibition (24依2.3mm) against S. mutants and minimum zone of\udinhibition was observed with aqueous extract against P. aeruginosa (7依0.08). In addition the\udantibiotic sensitivity was observed with kanamycin, tetracyclin, ciprofloxacin against all\udbacterias. Conclusions: The methonalic extract of D. gangeticum be able to use as potential\udantibacterial source for various infective pathogens