Open AccessAntibacterial activity of medicinal plant Cyclea peltata (Lam) Hooks & Thoms
Author(s) -
Jyothi Abraham,
T. Dennis Thomas
Publication year - 2012
Publication title -
asian pacific journal of tropical disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.208
H-Index - 33
ISSN - 2222-1808
DOI - 10.1016/s2222-1808(12)60166-2
Subject(s) - petroleum ether , klebsiella pneumonia , antibacterial activity , minimum inhibitory concentration , staphylococcus aureus , chemistry , traditional medicine , ethyl acetate , agar diffusion test , proteus vulgaris , bacteria , acetone , chloroform , microbiology and biotechnology , biology , antimicrobial , chromatography , biochemistry , extraction (chemistry) , medicine , genetics
Objective: To investigate the antibacterial activity of Padathaali (Cyclea peltata) against three\udgram positive and eight gram negative bacterial strains. Methods: The fresh whole plants were\udcollected from Kerala, India. The dry crude nonpolar and polar extract of whole plant of C.\udpeltata i. e. Petroleum ether, hexane, chloroform, ethyl acetate, acetone, methanol and aqueous\udextracts of five concentrations (1, 2, 5, 10 mg/ml) were used to investigate the antibacterial\udactivity. NCCL standards were strictly followed to perform antibacterial disc susceptibility test\udusing disc diffusion method. Results: All the extracts showed varying degree of inhibitory\udpotential against all the tested bacteria. Methanol extract of plant had higher inhibitory action\udagainst Staphylococcus aureus, Streptococcus haemolyticus, Klebsiella pneumonia and Proteus\udvulgaris. Acetone extract of plant showed maximum inhibitory action against Klebsiella\udpneumonia and Streptococcus haemolyticus. Conclusions: The present investigation showed\udthe effectiveness of crude extract of this plant against tested bacterial strains. This study further\udsuggests the use of whole plant extract in treating disease caused by tested microbial organisms