Open AccessIn vitro antidiabetic activity of psidium guajava leaves extracts
Author(s) -
Sabjan Khaleel Basha,
Vinoji Sugantha Kumari
Publication year - 2012
Publication title -
asian pacific journal of tropical disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.208
H-Index - 33
ISSN - 2222-1808
DOI - 10.1016/s2222-1808(12)60131-5
Subject(s) - psidium , chemistry , ethanol , in vitro , traditional medicine , methanol , ic50 , chromatography , biochemistry , botany , biology , medicine , organic chemistry
Objective: To evaluate the glucose uptake of (antidiabetic activity) crude n-hexane, ethanol,\udethanol and aqueous leaf extracts of P.guajava. Methods: P.guajava leafextracts were subjected\udto inhibitory effect of glucose utilization using specific standard in vitro procedure. Results:\udresults in four different leaf extracts revealed that, the methanol extract at a concentration of\ud50g plant extract/l was found to be more potent than other extracts with the lowest mean glucose\udconcentration of 201+1.69 mg/dl at the end of 27 hrs. Conclusions: The present findings suggest\udthat, the methanolic extract showed a significant inhibitory effect on glucose diffusion in vitro\udthus validating the traditional claim of the plant