Open AccessAn In vitro studies on indigenous ayurvedic plants, having hypoglycemic activity
Author(s) -
Sushil Kumar Middha,
Talambedu Usha,
P. Tripathi,
Kirti Yashwant Marathe,
Tarun Jain,
Bhargavi Bhatt,
Yogini Pradeep Masurkar,
Veena Pande
Publication year - 2012
Publication title -
asian pacific journal of tropical disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.208
H-Index - 33
ISSN - 2222-1808
DOI - 10.1016/s2222-1808(12)60122-4
Subject(s) - momordica , trigonella , traditional medicine , punica , syzygium , herb , medicinal plants , indigenous , medicine , nigella sativa , chemistry , biology , medicinal herbs , ecology
Objective: Finding a cure for diseases and infections using herbal medicines are as old as\udmankind. The present study aimed at investigation of anti-hyperglycemic potential of methanolic\udextract of some indigenous ayurvedic plants used in Karnataka. Design setting: There are a few\udexplicit studies to confirm invitro hypoglycemic activity. Our work is based on the study of some\udindigenous plants which show inhibitory effect on glucose oxidase and are in use as hypoglycemic\udagents in traditional system of medicine. Result: Syzygium cumini , Trigonella foenum graecum\udseed, Moringa alba leaf, Punica granatum peel, Emblica officinalis and Momordica charantia\udpossessed highest hypoglycemic activity of varying degree. S. cumini and T. foenum had shown\udthe better activity in neutral and basic media than others. Whereas, Alterathera ficoicka leaf, T.\udfoenum and Momordica charantia have shown prominent result in acidic media. The result in\udthree different media revealed that, acidic medium shows less prominent hypoglycemic activity\udas compared to neutral and basic medium. Conclusion: S. cumin, T. foenum seed and M.\udcharantia gave the impression of being prominent candidates for drug targets for diabetes. This\udmay be the first report using invitro approach to prove their antidiabetic properties