Open AccessAdulticidal activity of Ageratum houstonianum Mill. (Asteraceae) leaf extracts against three vector mosquito species (Diptera: Culicidae)
Author(s) -
John Ravindran,
T Samuel,
Edah O. Alex,
John William
Publication year - 2012
Publication title -
asian pacific journal of tropical disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.208
H-Index - 33
ISSN - 2222-1808
DOI - 10.1016/s2222-1808(12)60042-5
Subject(s) - anopheles stephensi , culex quinquefasciatus , aedes aegypti , bioassay , biology , ethyl acetate , mosquito control , phytochemical , traditional medicine , aedes , toxicology , botany , veterinary medicine , larva , malaria , medicine , biochemistry , genetics , immunology
To determine the intrinsic toxicity of hexane, ethyl acetate and methanol crude extracts\udof Ageratum houstonianum leaves against adult Anopheles stephensi, Aedes aegypti and Culex\udquinquefasciatus mosquitoes. Methods: Bioassay was performed in 2-day-old laboratory reared\udunfed adult female mosquitoes by topical application at concentrations of 0.01, 0.05, 0.10, 0.25 and\ud0.50 毺 g/mg female adult mosquito. Results: Aedes aegypti was found to be more susceptible to ethyl\udacetate and hexane extracts with LD\ud50 value of 0.10 毺 g/mg, and both Anopheles stephensi and Culex\udquinquefasciatus were susceptible to methanol extract with LD50 values of 0.12 毺 g/mg female adult\udmosquito. Conclusions: The results show promising adulticidal activity on topical application and\udfurther studies followed by in-depth laboratory and field bioassays are needed to screen, isolate and\udpurify bioactive phytochemical constituents or compounds