Open AccessIs jaundice a prognosis of leptospirosis?
Author(s) -
Manisha DebMandal,
Sandip Mandal,
Nishith Kumar Pal
Publication year - 2011
Publication title -
asian pacific journal of tropical disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.208
H-Index - 33
ISSN - 2222-1808
DOI - 10.1016/s2222-1808(11)60065-0
Subject(s) - leptospirosis , jaundice , transaminase , medicine , gastroenterology , leptospira , incidence (geometry) , bilirubin , creatinine , veterinary medicine , biology , enzyme , biochemistry , physics , optics
Objective: To determine the incidence of leptospiral jaundice and find the correlation among\udhuman leptospiral cases with or without jaundice. Methods: Patients suspected for leptospirosis,\udattending Calcutta School of Tropical Medicine, Kolkata, India during 2002 to 2008 were evaluated\udas per modified Faine ’s criterion. Results: Out of 404 suspected cases, 214 were found positive\udfor leptospirosis, 15 were jaundice positive but without leptospirosis and 175 cases had neither\udleptospirosis nor jaundice. Serum bilirubin and creatinine levels among leptospirosis patients were\ud(1.89-42.70 mg/dL) and (0.60-6.40 mg/dL), respectively; serum glutamic-oxaloacetic transaminase\ud(SGOT) and serum glutamic pyruvic transaminase (SGPT) were (99.00-410.00 U/L) and (57.00-887.00\udU/L), respectively; IgM values by ELISA were (0.63-3.28 U/mL). Conclusions: There is no\udassociation between occurrence of jaundice and leptospirosis and it also does not confirm the\udexpected 1:1 ratio of jaundice and leptospirosis (P<0.005)