Open AccessFight malaria at home: Therapeutic and prophylaxis clinical data
Author(s) -
D. K. Bhattacharya
Publication year - 2011
Publication title -
asian pacific journal of tropical disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.208
H-Index - 33
ISSN - 2222-1808
DOI - 10.1016/s2222-1808(11)60055-8
Subject(s) - malaria , medicine , plasmodium falciparum , punica , traditional medicine , drug , indigenous , cerebral malaria , pharmacology , biology , immunology , ecology
Objective: To identify a new, safe and effective source to combat and prevent drug resistant\udmalaria therapeutically and to make it as a home-made bio-medicine which is called as\udOMARIA (Orissa malaria research indigenous attempt) and use it on long term basis (decade)\udin mono clinical station and in field. Methods: The rind of a lesser known Indian indigenous\udfruit dalimba/ Punica granatum (P. granatum) is taken. Manual process to make a hand-made\udor home-made bio-medicine is done. Hand-filled into gelatin capsules and administered as\udan internal medicine. Therapy to 532 clinical cases is given at the Govt Red Cross Clinic, and\udProphylaxis at site is administered to 401 cases by adopting 3 villages. Results: Hydrophyllic,\udellagitannins viz., punicalagin (C 48H28O 30; mw 1 1 00~1 1 25), punicalin (C 34H22O 22; mw 780~785),\udellagic acid (C14H6O8; mw 302) and K+ co-exists as the only drug moieties. OMARIA has no other\udconfounding or confabulating compounds. There is non alkaloid. Conclusions: OMARIA delivers\udtherapeutics and prophylaxis to drug resistant Plasmodium falciparum (P. falciparum) cases.\udThere are no side effects and no contradictions. Non-toxic at bolus/loading doses. No case\udprogressed to cerebral malaria. OMARIA is a first time work. Original report on pan global basis