Open AccessLipid ratio useful indicator in predicting risk of myocardial infarction in elderly normolipidemic patients: a report from a multi center study
Author(s) -
Arun Kumar,
Utpal Kumar Biswas,
Suryakant Nagtilak,
R. Sivakanesan
Publication year - 2011
Publication title -
asian pacific journal of tropical disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.208
H-Index - 33
ISSN - 2222-1808
DOI - 10.1016/s2222-1808(11)60051-0
Subject(s) - myocardial infarction , medicine , cholesterol , lipid profile , cardiology , coronary heart disease , endocrinology
Objective: To evaluate the usefulness of lipid ratios in predicting coronary heart disease risk in\udnormolipidaemic myocardial infarct (MI) patients and compare the findings with healthy controls.\udMethods: Lipid profile was determined in 1 021 normolipidaemic myocardial infarct patients\udand was compared with 1 021 age/sex-matched controls. Total cholesterol (TC), triglycerides (TG)\udand HDL-cholesterol (HDL-C) were analyzed enzymatically using kits obtained from Randox\udLaboratories Limited, Crumlin, UK. Plasma LDL-cholesterol (LDL-C) was determined from the values\udof TC and HDL-C using the friedwald ’s formula. The values were expressed as mean暲SD and data\udfrom patients and controls were compared using students' t-test. Results: TC, TC/HDL-C ratio,\udTG, LDL-C, LDL-C/HDL-C ratio were higher in MI patients (P<0.001). HDL-C concentration was\udsignificantly lower in MI patients than controls (P<0.001). Higher ratio of TC/HDL-C, TG/HDL-C\udand LDL-C/HDL-C was observed in acute myocardial infarct patients as compared with controls.\udConclusions: Establishment of lipid ratio from routine lipid profile assay could be very useful in\udpredicting the future risk of acute mocardial infarction