Open AccessJapanese encephalitis epidemiology in Arunachal Pradesh, a hilly state in northeast India
Author(s) -
SA Khan,
Prafulla Dutta,
Aftab Aslam Parwaz Khan,
Rashmee Topno,
Pritom Chowdhury,
Jani Borah,
Jagadish Mahanta
Publication year - 2011
Publication title -
asian pacific journal of tropical disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.208
H-Index - 33
ISSN - 2222-1808
DOI - 10.1016/s2222-1808(11)60050-9
Subject(s) - japanese encephalitis , vaccination , medicine , veterinary medicine , population , epidemiology , virology , encephalitis , serology , virus , traditional medicine , demography , environmental health , antibody , immunology , sociology
Objective: To confirm Japanese encephalitis (JE) cases from the state of Arunachal Pradesh\ud(AP), India for the first time. Methods: Suspected acute encephalitis syndrome (AES) cases were\udscreened from 2005-2010. The cases were initially tested for antibodies against JE by using IgM\udMAC ELISA kits (National Institute of Virology, Pune). RNA was extracted from the cerebrospinal\udfluid (CSF) samples followed by molecular amplification of JE virus specific gene primer. The data\udobtained were used to calculate relative risks between the age groups and between the genders.\udEpi info 6.0 was used for the statistical analysis. Results: Presence of JE cases in the state of\udAP, India was established. JE cases from 10 out of 16 districts were recorded. As part of control\udand preventive measures, mass vaccination for children (0-15 years) by SA-14-14-2 JE vaccine\udwas taken up in 2010 in the district of Lohit. Vaccination coverage of 83.09% among the target\udpopulation was achieved. Conclusions: The study presents the first report of confirmed JE cases\udfrom the state of AP, India. This finding attracts attention as JE cases are rarely seen to occur in\udhilly places