Open AccessDetection of metallo β-lactamase producing Klebsiella pneumoniae in a neonatal septicemia
Author(s) -
Debasmita Dubey,
Rachita Sarangi,
Nagen Kumar Debata,
Rabindra N. Padhy
Publication year - 2013
Publication title -
journal of acute disease
Language(s) - English
Resource type - Journals
eISSN - 2589-5516
pISSN - 2221-6189
DOI - 10.1016/s2221-6189(13)60104-3
Subject(s) - klebsiella pneumoniae , meropenem , medicine , imipenem , microbiology and biotechnology , lethargy , antibiotics , antibiogram , antibiotic resistance , biology , escherichia coli , biochemistry , gene
AbstractA 10-day old preterm neonate, appropriate for the date, was admitted for lethargy and feeding intolerance. By culturing its blood, the antibiogram of the causative bacterium was ascertained by both Kirby-Bauer disc diffusion method and the Vitek2 system. Due clinical steps were taken for survival of the baby. The baby was suffering from septicemia. The causative bacterium was Klebsiella pneumoniae (K. pneumoniae). The isolated strain was found resistant to a total of 17 antibiotics; the strain was positive for extended spectrum β-lactamase production and resistant to two carbapenems, imipenem and meropenem. The baby could not survive. The baby was infected with an appalling strain of K. pneumoniae with a capacity to produce metallo β-lactamase overriding carbapenems, which is found to present in the state of Odisha, India