z-logo
open-access-imgOpen Access
Acute Hepatitis Induced by Chinese Hepatoprotective Herb, Xiao-Chai-Hu-Tang
Author(s) -
Li-Ming Hsu,
Yi-Hsiang Huang,
ShyhHaw Tsay,
FullYoung Chang,
ShouDong Lee
Publication year - 2006
Publication title -
journal of the chinese medical association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.535
H-Index - 42
eISSN - 1728-7731
pISSN - 1726-4901
DOI - 10.1016/s1726-4901(09)70119-4
Subject(s) - medicine , decoction , traditional medicine , liver biopsy , herb , hepatitis , acute hepatitis , chai , gastroenterology , traditional chinese medicine , medicinal herbs , pathology , biopsy , alternative medicine , philosophy , theology
Xiao-chai-hu-tang (syo-saiko-to in Japanese) is a herbal remedy that has been widely used in China for treatment of respiratory, hepatobiliary, and gastrointestinal diseases, particularly among patients with chronic liver disease. However, its safety has recently been challenged. We, herein, report a Chinese patient with acute hepatitis induced by this herb. A 52-year-old woman presented with weakness, fatigue, and tea-colored urine after continual consumption of the decoction of xiao-chai-hu-tang for 1.5 months. Laboratory studies disclosed acute hepatitis even though all of the viral hepatitis markers were negative. Liver biopsy also revealed a picture of acute hepatocellular hepatitis. The symptoms improved after discontinuing the drug, and liver biochemical tests normalized 2 months later. The case report reminds us of the probable adverse drug reaction of herbs, even in some that are claimed to have hepatoprotective effects.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.
Having issues? You can contact us here