Open AccessNeurofibroma in the Left Mandible: A Case Report
Author(s) -
Tao Qian,
Wang Yi,
Zheng Chaoqun
Publication year - 2010
Publication title -
the kaohsiung journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.439
H-Index - 36
eISSN - 2410-8650
pISSN - 1607-551X
DOI - 10.1016/s1607-551x(10)70032-2
Subject(s) - neurofibroma , medicine , neurofibromatosis , mandible (arthropod mouthpart) , plexiform neurofibroma , fascicle , anatomy , pathology , immunohistochemistry , neurofibromatosis type i , biology , botany , genus
We report a rare case of isolated neurofibroma arising in the left mandible without family history of neurofibromatosis type 1. The tumor was histopathologically analyzed and an immunohistochemical panel comprising S‐100 protein was performed. Vim, HMB45, and HHF35 were negative. The tumor cells were fusiform in shape, arranged in a plexiform manner, and grew actively. Features typical of neurofibroma, including an enlarged nerve fascicle composed of elongated nuclei and scant cytoplasmic cells, were identified. Our study suggest that neurofibroma can occur in the jaw as an isolated benign tumor in patients without other features of neurofibromatosis type 1.