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Diabetic Muscle Infarction in Association with Terlipressin Therapy: A Case Report
Author(s) -
Chang YuHung,
Yen FengChieh,
Hsieh MingChia,
Lin KunDer,
Shin ShyiJang,
Hsin ShihChieh
Publication year - 2009
Publication title -
the kaohsiung journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.439
H-Index - 36
eISSN - 2410-8650
pISSN - 1607-551X
DOI - 10.1016/s1607-551x(09)70036-1
Subject(s) - medicine , terlipressin , cirrhosis , infarction , surgery , complication , muscle biopsy , magnetic resonance imaging , biopsy , radiology , myocardial infarction , hepatorenal syndrome
Diabetic muscle infarction (DMI) is a rare complication that often exists in long‐standing diabetic patients. Clinically, it presents with pain, swelling and sometimes a palpable mass, and is often misdiagnosed as soft tissue infection. The athogenesis of DMI is uncertain. We present the case of a type 2 diabetic patient with liver cirrhosis who was diagnosed with muscle infarction after being treated with terlipressin for gastrointestinal bleeding. This 45‐year‐old male complained of increasing pain in his right posterior thigh after treatment with terlipressin for 2 days. He was initially diagnosed with soft tissue infection, but he responded poorly to antibiotic treatment. Magnetic resonance imaging suggested acute muscle infarction. We performed a muscle biopsy and the pathologist reported that the muscle was necrotic. After 5 days of bed rest, the patient was able to walk and was discharged uneventfully.

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