Open AccessDiffusion‐weighted Magnetic Resonance Imaging of the Liver in Hepatitis B Patients with Child‐Pugh A Cirrhosis
Author(s) -
Hsu FengO,
Chiou YenYu,
Chen ChiaoYun,
Liu GinChung,
Chu HuiChen,
Liu HuiCheng,
Chu HuiMin,
Hsu JuiSheng
Publication year - 2007
Publication title -
the kaohsiung journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.439
H-Index - 36
eISSN - 2410-8650
pISSN - 1607-551X
DOI - 10.1016/s1607-551x(08)70051-2
Subject(s) - medicine , cirrhosis , magnetic resonance imaging , hepatitis , acute hepatitis , gastroenterology , effective diffusion coefficient , hepatitis b , radiology
The purpose of this study was to test the hypothesis that cirrhotic change of liver in hepatitis B patients observed in Child‐Pugh classification based on clinical assessment would be reflected in the apparent diffusion coefficient (ADC) values calculated from diffusion‐weighted magnetic resonance (MR) imaging. Twenty‐seven patients with hepatitis B Child‐Pugh class A cirrhosis and 10 control subjects were referred for measurement values of the liver on a 3.0‐T MR unit. The results revealed that ADCs were significantly lower in hepatitis B patients with Child‐Pugh class A compared with control subjects (p<0.01). In conclusion, our preliminary study showed that hepatitis B patients with Child‐Pugh class A had reduced ADC values in liver vis‐a‐vis normal subjects.