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An Unexpected Adverse Drug Effect
Author(s) -
Krulewitch Cara J.
Publication year - 2003
Publication title -
journal of midwifery and women's health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.543
H-Index - 62
eISSN - 1542-2011
pISSN - 1526-9523
DOI - 10.1016/s1526-9523(02)00361-6
Subject(s) - adverse effect , drug , metronidazole , disulfiram , medicine , pharmacology , mechanism (biology) , intensive care medicine , antibiotics , chemistry , biochemistry , philosophy , epistemology
Adverse drug‐drug interactions can occur between active and/or inactive ingredients in different formulations. The occurrence of a disulfiram reaction that developed postpartum following a 7‐day course of metronidazole is presented. The case is presented, followed by a discussion of the mechanism of action and treatment. Recommendations for prevention of adverse drug effects are reviewed.