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Acute cardiac failure in neuroleptic malignant syndrome ☆
Author(s) -
Sparrow Patrick,
Murnaghan Dermot,
Kearney Peter,
Hogan John,
Sheppard Mary N.
Publication year - 2003
Publication title -
european journal of heart failure
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.149
H-Index - 133
eISSN - 1879-0844
pISSN - 1388-9842
DOI - 10.1016/s1388-9842(03)00036-9
Subject(s) - medicine , heart failure , neuroleptic malignant syndrome , disease , cardiology , thioridazine , necrosis , histology , pathology , chlorpromazine
We present a case of rapid onset acute cardiac failure developing as part of Neuroleptic malignant syndrome in a 35‐year‐old woman following treatment with Thioridazine and Lithium. Post mortem histology of cardiac and skeletal muscle showed similar changes of focal cellular necrosis and vacuolation suggesting a common disease process.