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Radiological Morphometric Analysis for the Trabecular Bone Structure of Mandibular Condyle after Ovariectomy in Mature Cynomolgus Monkeys
Author(s) -
Shimamoto Michiharu,
Kozai Yusuke,
Matsumoto Yukiko,
Kawamata Ryota,
Sakurai Takashi,
Kashima Isamu
Publication year - 2007
Publication title -
oral science international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.256
H-Index - 13
eISSN - 1881-4204
pISSN - 1348-8643
DOI - 10.1016/s1348-8643(07)80003-6
Subject(s) - condyle , osteoporosis , radiography , medicine , magnification , temporomandibular joint , anatomy , trabecular bone , bone mineral , cortical bone , dentistry , radiology , computer science , computer vision
To investigate the effects of experimental osteoporosis on the trabecular structure of the mandibular condyle in cynomolgus monkeys by radiological bone morphometry, ovariectomy (OVX) was performed on 10‐year‐old female cynomolgus monkeys, which were fed a controlled diet for 2 years. Ten sham control groups were fed under the same conditions. Using a microfocus tube and computed radiography, the removed mandibular condyle samples were imaged by standardized magnification radiography. The structural parameters were measured using radiological bone morphometric analysis. The bone mineral density (BMD) was measured by dual energy X‐ray absorptiometry. The thickness of the cortical bone was measured using magnified radiographic images. The thickness of the cortical bone and the BMD in the OVX group were significantly lower than in the sham group. In the results of skeletal structure of the mandibular condyle, the trabecular structure of the mandibular condyle was markedly deteriorated in the OVX group. The trabecular structure of the mandibular condyle for the OVX group was significantly decreased, thus it was suggested that osteoporosis is a potential risk factor of osteoarthritis of the temporomandibular joint.