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Redistribution and unmasking of Annexin V binding sites in apoptotic Raji cells
Author(s) -
Certo Maria Grazia,
Faggioni Alberto,
Barile Giuseppe
Publication year - 2003
Publication title -
cell biology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.932
H-Index - 77
eISSN - 1095-8355
pISSN - 1065-6995
DOI - 10.1016/s1065-6995(03)00074-x
Subject(s) - redistribution (election) , annexin , apoptosis , microbiology and biotechnology , raji cell , annexin a5 , annexin a2 , chemistry , biology , cell , biochemistry , political science , politics , law
Abstract The complement receptor type 2 (CR2) associates with other surface antigens and proteins and its redistribution and/or unmasking occurs through still unknown mechanism(s). The data presented demonstrate that high‐density cultured CR2‐positive cells undergo apoptosis and that the redistribution and unmasking of Annexin V binding sites occurs in a fashion similar to the redistribution and unmasking of CR2. Therefore, apoptotic and non apoptotic cells from the same lineage may share a similar mechanism for the exposition of neo‐surface markers