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Effect of a single neonatal endorphin treatment on the hormone content of adult rat white blood cells and mast cells
Author(s) -
Csaba György,
Kovács Péter,
Pállinger Éva
Publication year - 2003
Publication title -
cell biology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.932
H-Index - 77
eISSN - 1095-8355
pISSN - 1065-6995
DOI - 10.1016/s1065-6995(03)00034-9
Subject(s) - medicine , endocrinology , hormone , serotonin , mast cell , flow cytometry , histamine , biology , mast (botany) , imprinting (psychology) , chemistry , immunology , receptor , biochemistry , gene
Using flow cytometry and confocal microscopy, the presence of endorphin, serotonin and chorionic gonadotropin (hCG) was demonstrated in rat white blood cells and peritoneal mast cells. After a single neonatal treatment with β‐endorphin (hormonal imprinting), the mast cells of female rats reaching adulthood contained significantly less endorphin and serotonin, as well as slightly less hCG, than control cells. There was no change in the hormone content of the mast cells of males. The lymphocytes, monocytes and granulocytes of both sexes also contained the three hormones, but endorphin imprinting had no effect on these cells.