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Perinatal characteristics and schizophrenia : electrodermal activity as a mediating link in a vulnerability‐stress perspective
Author(s) -
Hultman Christina M.,
Öhman Arne
Publication year - 1998
Publication title -
international journal of developmental neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.761
H-Index - 88
eISSN - 1873-474X
pISSN - 0736-5748
DOI - 10.1016/s0736-5748(98)00027-6
Subject(s) - schizophrenia (object oriented programming) , vulnerability (computing) , perspective (graphical) , psychology , developmental psychology , environmental stress , neuroscience , psychiatry , biology , computer security , artificial intelligence , computer science , ecology
Vulnerability‐stress models of schizophrenia assert that the disorder results from an interaction between genetic or biologically acquired vulnerability and unfavourable environmental conditions. As our knowledge of early environmental factors for schizophrenia evolves, the question of links between early factors and a development of schizophrenia becomes more important. In this article, we analyse the relationship between obstetrical complications (OCs) and adult schizophrenia and methodological concerns in the search for pre‐ and perinatal risk factors. We review findings of aberrant electrodermal activity in schizophrenic patients and suggest that OCs may induce insults to cerebral structures that are critically involved in the control of orienting and of autonomic responses.