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Effect of high‐intensity running in rectus femoris muscle fiber in rats
Author(s) -
DíazHerrera Pilar,
GarcíaCastellano José M.,
Torres Ana,
Morcuende José A.,
Calbet José A. L.,
Sarrat René
Publication year - 2001
Publication title -
journal of orthopaedic research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.041
H-Index - 155
eISSN - 1554-527X
pISSN - 0736-0266
DOI - 10.1016/s0736-0266(00)00031-0
Subject(s) - rectus femoris muscle , fiber type , skeletal muscle , muscle fibre , treadmill , atrophy , medicine , oxidative phosphorylation , chemistry , physical therapy , endocrinology , physical medicine and rehabilitation , anatomy , electromyography , biochemistry
The effect of a 12‐week high‐intensity intermittent exercise program on fiber type composition and the oxidative capacity of rectus femoris skeletal muscle from 20 male Wistar rats (Trained, n = 10; Sedentary, n = 10) was histochemically determined. The training exercise program was developed in a motorized treadmill. It consisted of four running bouts of 2 min duration at 48 m/min, alternated with recovery intervals of 4 min. Training increased relative cross‐sectional area of oxidative fibers (I, IIA, IIX) and decreased the same parameter in type IIB non‐oxidative fibers ( P < 0.001). Our results suggest that this type of strength exercise program is enough to induce changes in muscle fiber composition. This opens a possibility to use this kind of exercise in preventing and treating muscle atrophy. © 2001 Orthopaedic Research Society. Published by Elsevier Science Ltd. All rights reserved.