Open AccessThe TH17 vs. TREG Imbalance in the Pathogenesis of Periodontitis: New Approach for Dichotomy TH1 vs. TH2
Author(s) -
Andrea Dezerega,
S Maggiolo,
Mauricio Garrido,
Nicolás Dutzan
Publication year - 2008
Publication title -
revista clínica de periodoncia, implantología y rehabilitación oral
Language(s) - English
Resource type - Journals
eISSN - 0719-0107
pISSN - 0718-5391
DOI - 10.1016/s0718-5391(08)70012-0
Subject(s) - periodontitis , immunology , pathogenesis , immune system , subject matter , disease , medicine , neuroscience , biology , psychology , pathology , pedagogy , curriculum
For decades several authors have directed their efforts to elucidate the nature of the immune response in periodontitis. The subject has been matter of controversy, and answers remain unclear. The present review intends to summarize the character of the inflammatory response in periodontitis, with emphasis on the T helper imbalance produced during the development of the disease