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Lithium induces changes in the plasma membrane protein pattern of early amphibian embryos
Author(s) -
Lazou Antigone,
Beis Androniki
Publication year - 1993
Publication title -
biology of the cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 85
eISSN - 1768-322X
pISSN - 0248-4900
DOI - 10.1016/s0248-4900(05)80197-2
Subject(s) - biology , amphibian , embryo , lithium (medication) , microbiology and biotechnology , membrane , biophysics , biochemistry , ecology , endocrinology
Summary— The plasma membrane protein pattern of Rana ridibunda embryos subjected to lithium (Li) treatment at various stages of development was examined by two‐dimensional gel electrophoresis. Differences were observed at the neurula stage not only as compared to controls but among lithium‐treated embryos as well. Of particular interest was the presence of proteins, specific for the gastrula stage, in lithium‐treated embryos. The results are discussed in relation to the well‐known effect of lithium on amphibian morphogenesis.