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New perspectives on mitochondrial morphology in cell function
Author(s) -
Brocard Jacques B.,
Rintoul Gordon L.,
Reynolds Ian J.
Publication year - 2003
Publication title -
biology of the cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 85
eISSN - 1768-322X
pISSN - 0248-4900
DOI - 10.1016/s0248-4900(03)00062-5
Subject(s) - biology , mitochondrion , microbiology and biotechnology , intracellular , function (biology) , morphology (biology) , cell , cell function , programmed cell death , apoptosis , biochemistry , genetics
Mitochondria are a node of integration for intracellular signaling pathways and their morphology changes seem to be tightly associated with their function. New data show that morphology is one of the parameters involved in mitochondria's choice between promoting cell death and protecting cells against general metabolic jeopardy.