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Molecular characterization of a defensin in the IZD‐MB‐0503 cell line derived from immunocytes of the insect Mamestra brassicae (Lepidoptera)
Author(s) -
Mandrioli Mauro,
Bugli Silvia,
Saltini Sabrina,
Genedani Susanna,
Ottaviani Enzo
Publication year - 2003
Publication title -
biology of the cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 85
eISSN - 1768-322X
pISSN - 0248-4900
DOI - 10.1016/s0248-4900(02)01219-4
Subject(s) - lepidoptera genitalia , biology , defensin , bacteria , insect , microbiology and biotechnology , biochemistry , botany , genetics , antimicrobial
The induction of anti‐microbial peptides against Gram positive and negative bacteria in the IZD‐MB‐0503 cell line from the lepidopteran Mamestra brassicae is demonstrated, while no anti‐fungal activity is detected. The identification of a defensin‐like molecule active against Gram positive bacteria is described for the first time in Lepidoptera. This molecule shows between 43% and 59% homology with group A defensins from other dipteran and hymenopteran species.