Open AccessSíndrome de Brugada
Author(s) -
María Lucía Padrón Hernández,
Hugo Fernando Pérez Reyes
Publication year - 2014
Publication title -
revista pediatría/pediatria
Language(s) - English
Resource type - Journals
eISSN - 2444-9369
pISSN - 0120-4912
DOI - 10.1016/s0120-4912(15)30127-0
Subject(s) - brugada syndrome , medicine , humanities , cardiology , j wave , sudden death , sudden cardiac death , philosophy
Brugada syndrome is a channelopathy that predisposes to ventricular arrhythmias, and sudden death in the absence of structural heart disease. It was first described in the early nineties, and significant progress has been made understanding its physiopathology, seeking an early diagnosis.Alterations in the ionic currents during the initial phases of the action potential in cardiac myocytes generate a potentially arrhythmogenic transmural gradient with characteristic electrocardiographic changes in right precordial leads, consisting of elevation of the ST segment, and variations of the T wave.This syndrome should always be suspected in pediatric patients that come to the emergency room with a syncope, because it may be the first clinical manifestation of the Brugada syndrome