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Sonographic diagnosis of intrauterine growth restriction (IUGR) by fetal transverse cerebellar diameter (TCD)/abdominal circumference (AC) ratio
Author(s) -
Tongsong T.,
Wanapirak C.,
Thongpadungroj T.
Publication year - 1999
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/s0020-7292(99)00056-9
Subject(s) - medicine , obstetrics , gestational age , intrauterine growth restriction , gestation , receiver operating characteristic , fetus , percentile , prospective cohort study , pregnancy , mathematics , statistics , genetics , biology
Objective: To evaluate the validity of TCD/AC ratio in predicting IUGR. Study design: Prospective descriptive analysis. Setting: Maharaj Nakorn Chiang Mai Hospital, Chiang Mai University. Subjects: Women meeting the inclusion criteria consisting of: (1) singleton pregnancies after 28 weeks of gestation; (2) known accurate gestational age; and (3) clinically suspected IUGR. Methods: The patients were sonographically examined for TCD/AC ratio. The best cut‐off value of TCD/AC ratio in predicting IUGR was determined by a receiver operating characteristic (ROC) curve. The fetus with a TCD/AC ratio greater than the cut‐off value would be antenatally diagnosed as IUGR for every gestational week. Standard definition of IUGR was a low birthweight, less than the l0 th percentile. Results: One hundred and sixty‐seven pregnancies with suspected IUGR were analyzed. The prevalence of IUGR among the study group was 51.5%. The best cut‐off value of the TCD/AC ratio for predicting IUGR was 15.4%, giving the sensitivity, specificity, positive predictive value and negative predictive value of 73.26%, 80.25%, 79.75%, and 73.86%, respectively. Conclusion: The sonographic fetal TCD/AC ratio as a gestational age‐independent method can be helpful in antenatal diagnosis of IUGR, especially in pregnancy with uncertain gestational age.