Premium
Color Doppler energy and related quantitative analysis of gestational trophoblastic tumors
Author(s) -
Xie H.,
Hata K.,
Lu M.,
Kong Q.,
Miyazaki K.
Publication year - 1999
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/s0020-7292(99)00033-8
Subject(s) - medicine , trophoblastic tumor , gynecology , blood flow , gestational age , color doppler , obstetrics , gestation , chorioepithelioma , pregnancy , chemotherapy , choriocarcinoma , radiology , ultrasonography , genetics , biology
Objective: To assess the reliability of color Doppler energy (CDE) and a related quantitative analysis for detection and follow‐up of uterine involvement in gestational trophoblastic tumor. Method: CDE was performed in 19 patients with trophoblastic tumor, in 25 women in early pregnancy and 25 non‐pregnant women. The blood flow area ratio (BFAR) in CDE was used as an index representing uterine involvement. In nine of the 19 patients, BFAR was measured before, during and at termination of chemotherapy. Result: The BFAR (mean±S.D.) of uterine profiles in 19 patients (39.9±1.3%) was significantly higher than that in 25 pregnant women (24.6±10.1%, P =0.002) and in 25 non‐pregnant women (14.8±5.7%, P =0.001). In the follow‐up of nine patients, when β‐hCG was less than 3.1 ng/ml during the treatment, the BFAR (38.7±11.9%) decreased below that (44.2±14.6%) seen prior to treatment ( P =0.009) and was much lower at termination of treatment (27.5±12.3%, P =0.048). Conclusion: These data support the use of CDE and the related quantitative analysis as a new method for detecting and follow‐up of uterine involvement in patients with trophoblastic tumors.