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Fetal middle‐cerebral and umbilical artery flow assessments after glucose challenge test
Author(s) -
Pardo J.,
Orvieto R.,
Rabinerson D.,
Bar J.,
Hod M.,
Kaplan B.
Publication year - 1999
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/s0020-7292(99)00026-0
Subject(s) - medicine , umbilical artery , middle cerebral artery , fetus , ingestion , cerebral arteries , cerebral blood flow , blood flow , anesthesia , pregnancy , biology , genetics , ischemia
Objective : To determine whether a change occurs in fetal middle‐cerebral and umbilical artery flow after glucose challenge testing. Method : Fetal middle‐cerebral and umbilical artery flow was assessed by Color Dopppler technology in 21 pregnant patients before and after the 50‐g glucose challenge test. The resistance index (IR) was evaluated separately for each vessel. Statistical significance was determined by Chi‐square test and repeated measurement analysis with two co‐variates. Results : After glucose ingestion the RI was significantly decreased in the middle‐cerebral artery, but not in the umbilical artery. A significant increase in RI was recorded in the umbilical artery when maternal plasma glucose level exceeded 102 mg%. Conclusion : Maternal ingestion of glucose significantly alters blood flow velocimetry in the fetal middle‐cerebral and umbilical arteries. These changes may lead to the misinterpretation of normal results. It is therefore recommended that sonographic flow velocimetry assessment not be performed early after concentrated glucose ingestion.