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Effect of cigarette smoke on human placenta morphometry
Author(s) -
Rocha J.E.S,
Matheus M,
Sala M.A
Publication year - 1998
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/s0020-7292(98)00107-6
Subject(s) - medicine , placenta , cigarette smoke , stereology , trophoblast , cigarette smoking , fetus , obstetrics , andrology , pregnancy , physiology , pathology , biology , genetics , environmental health
Objective: To evaluate the placental alterations in smoking mothers. Method: A case‐control stereologic study of 10 placentas from smokers and 10 from non‐smokers. Result: The authors found a significant increase in stromal volume density, villus size and trophoblast thickness, and a significant decrease in villus and vessel surface densities, total surfaces, and number/mm 2 histological field in the smokers' placenta. Conclusions: The alterations found in the smokers' placenta greatly contribute to impairing the exchanges between maternal and fetal blood.