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Single dose methotrexate therapy: application to interstitial ectopic pregnancy
Author(s) -
Borgatta L,
Burnhill M,
Stubblefield P
Publication year - 1998
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/s0020-7292(97)00274-9
Subject(s) - medicine , methotrexate , ectopic pregnancy , interstitial pregnancy , gestational sac , obstetrics , medical treatment , pregnancy , medical therapy , antifolate , antimetabolite , gynecology , surgery , intensive care medicine , genetics , biology
A woman with a small (6‐mm gestational sac) interstitial pregnancy had complete resolution after medical therapy alone. A single cycle of methotrexate 50 mg/m 2 was used as outpatient treatment without any operative procedure either for diagnosis or intervention. The guidelines that have evolved for selection of women for single dose methotrexate treatment for both intrauterine and tubal ectopic pregnancies may be applicable to interstitial ectopic pregnancy as well. A suggested framework for treatment decisions is presented.