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Gestational diabetes mellitus and glucose intolerance in a Mexican population
Author(s) -
Forsbach G,
CantúDiaz C,
VázquezLara J,
VillanuevaCuellar M.A,
Alvarez y Garcı́a C,
Rodrı́guezRamı́rez E
Publication year - 1997
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/s0020-7292(97)00221-x
Subject(s) - medicine , gestational diabetes , hypoglycemia , diabetes mellitus , gestation , obstetrics , population , pregnancy , neonatal hypoglycemia , endocrinology , biology , genetics , environmental health
Objective: To determine the prevalence of gestational diabetes mellitus (GDM), glucose intolerance (GI) and macrosomia in a Latin Mexican population, using the one‐step procedure proposed by the World Health Organization. Method: Consecutive pregnant women ( n =667) who attended the antenatal clinic and delivered at the hospital were recruited after 24 weeks of gestation, mean 34.2 weeks, range 24–40 weeks. After a minimum of 3 days with a 150‐g carbohydrate diet, a glucose load of 75 g was administered and 2 h after, a blood sample for glucose was taken, plasma was separated and immediately processed for glucose, using a glucose‐oxidase method. Results: Twenty women were diagnosed with GDM (3%), 87 had GI (13%) and 560 had a normal glucose response (84%). Macrosomia occurred in two (10%) of GDM, in nine (10.3%) of GI, and in 29 (5.4%) gravidas with a normal response, respectively. Only one of the macrosomic infants whose mother had GI, had neonatal hypoglycemia and hyperbilirubinemia. Conclusion: The overall prevalence of glucose abnormalities during pregnancy was 16%. GI in this group was associated to macrosomia at the same rate as GDM.