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Single‐dose systemic oral fluconazole for the treatment of vaginal candidiasis
Author(s) -
Kaplan B.,
Rabinerson D.,
Gibor Y.
Publication year - 1997
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/s0020-7292(97)00070-2
Subject(s) - medicine , fluconazole , vulvovaginal candidiasis , vaginitis , vaginal disease , dermatology , vagina , antifungal , surgery , gynecology
Objectives: To evaluate the acceptance of fluconazole given in a single oral dose, for the safe, effective treatment of vaginal candidiasis. Methods: A total of 428 patients who had a first or recurrent episode of vaginal candidiasis diagnosed clinically or by culture, were offered treatment with fluconazole by 40 primary care gynecologists who were unfamiliar with fluconazole treatment of vaginal candidiasis. The efficacy of this treatment was evaluated by both physicians and patients. Results: Most of the physicians (72%) and most of the patients (69%) found the drug effective in relieving or at least alleviating the signs and symptoms of the disease. The majority of patients (83.5%) rated it better than other drugs they had received for vaginitis in the past. No recurrences were noted at the 6‐week follow‐up. Conclusions: Fluconazole has been found effective by physicians and patients. Both physician willingness to use it and patient compliance are satisfactory.