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Oral or vaginal misoprostol for induction of labor
Author(s) -
Toppozada M.K.,
Anwar M.Y.M.,
Hassan H.A.,
ElGazaerly W.S.
Publication year - 1997
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/s0020-7292(96)02805-6
Subject(s) - medicine , misoprostol , labor induction , obstetrics , induction of labor , gynecology , pregnancy , oxytocin , abortion , genetics , biology
Objective: To compare vaginal versus oral misoprostol for induction of labor. Method: Induction of labor was carried out in 40 women near term in two equal and randomized groups (according to a computer generated table) using misoprostol. Group I received vaginal misoprostol (100 μg) every 3 h while group II patients were given the same dose via the oral route. The dose was doubled if no response was detected under continuous cardiotocographic (CTG) tracings. Result: The vaginal route of administration induced a higher success rate in a shorter time interval using a lower dose but was associated with more abnormal FHR patterns and instances of uterine hyperstimulation. Conclusion: It is recommended to use the vaginal approach with cardiotocographic monitoring.