Premium
O108 A lower dose of magnesium sulphate for control of convulsion in eclamptic women of Bangladesh
Author(s) -
Begum K.
Publication year - 2009
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/s0020-7292(09)60480-x
Subject(s) - convulsion , magnesium , medicine , metallurgy , psychiatry , materials science , epilepsy
Eclampsia, a life threatening complication of pregnancy. It is one of the important cause of maternal mortality of Bangladesh. Eclamptic seizure can effectively controlled by use of magnesium sulphate. A prospective randomized case control study was conducted at eclampsia ward of Dhaka Medical College Hospital for one year from June 2007 to May 2008. Objective: To find out whether only 8gm of magnesium sulphate heptahydrate (Nalepsin) as a single loading dose is sufficient to control eclamptic convulsion and also to compare the efficacy between 8gm & 10gm of MgSo4 used to control convulsion. Methodology: A random selection was done by lottery of those antepartum and intrapartum cases who fulfill the selection criteria. Hundred patient were selected and grouped them into case & control. 8gm Nalepsion ( Magnesium sulphate heptahydrate) as a single I.V dose was selected for case and 10gm MgSo4 (4gm I.V + 3gm I.M in each buttock) was for control group. Different variables were compaired and results were analyzed by unpaired ‘t’ test and chi-square test (X2) by SPSS programme. Result: Statistically there was no significant difference of any finding between two groups after comparing all variables individually. Conclusion: 8gm Nalepsin intravenously as a single loading dose is sufficient to control eclamptic convulsion and prevention of its recurrence. 1. Assistant Prof. of Obstetrics & Gynae, Dhaka Medical College Hospital 2. Ex. Prof & Head of the Dept of Obstetrics & Gynae, Dhaka Medical College Hospital 3. Assistant Prof. of Obstetrics & Gynae, Dhaka Medical College Hospital 4. IMO, Dept of Obstetrics & Gynae, Dhaka Medical College Hospital Bangladesh J Obstet Gynaecol, 2010; Vol. 25(2) : 71-76