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Marie Stopes Society, Pakistan: 1000 cases of quinacrine sterilization (QS)
Author(s) -
Bilgrami M.,
Shah L.
Publication year - 2003
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/s0020-7292(03)90103-2
Subject(s) - medicine , sterilization (economics) , ectopic pregnancy , family planning , pregnancy , gynecology , obstetrics , pregnancy rate , female sterilization , research methodology , population , foreign exchange market , genetics , foreign exchange , environmental health , biology , monetary economics , economics
Objectives: To evaluate the safety, efficacy and acceptability of QS in Karachi, Pakistan. Methods: 1000 women who had chosen sterilization during the 4‐year period 1994 to 1997 inclusive were offered QS at both stationary clinics and in a mobile van at 23 sites in the outskirts of Karachi. The protocol involved transcervical insertion to the uterine fundus of 252 mg quinacrine in 7 pellets adn 55 mg of ibuprofen in 3 pellets through and IUD inserter, during the proliferative phase of the menstrual cycle. Two doses were administered one month apart. A temporary method of contraception was provided for 3 cycles, usually DMPA. Follow‐up was schedulre: monthly for 3 months, quarterly for 1 year and then every 6 months for 4 years. Results: The crude pregnancy rate after 4 years was 2.0%. Minor complications and complaints were reported by 59% of the patients. There was one ectopic pregnancy and no major complications. Conditions: QS was found to be safe and effective and has become the most popular method fo sterilization in our are of Pakistan.