Premium
Female sterilization with quinacrine using hysterosalpingography (HSG) as an endpoint after a single‐insertion protocol in Caracas, Venezuela
Author(s) -
Giugni Chalbaud A.,
Plaza Mora G.
Publication year - 2003
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/s0020-7292(03)90099-3
Subject(s) - hysterosalpingography , medicine , tubal occlusion , sterilization (economics) , occlusion , fallopian tube , female sterilization , surgery , intrauterine device , gynecology , research methodology , family planning , population , pregnancy , infertility , genetics , environmental health , monetary economics , economics , foreign exchange market , biology , foreign exchange
Objective: To evaluate the intrauterine insertion of quinacrine as an alternative nonsurgical female sterilization method by confirming bilateral occlusion of the fallopian tubes using HSG in a group of women who desire permanent sterilization. Methods: After doing hysterosalpingography to confirm patency of both fallopian tubes, 324 mg of quinacrine were introduced with a modified IUD inserter in 30 patients who came to Conceptión Palacios Maternity Hospital seeking permanent sterilization, between June 2000 and September 2001. Follow‐up with HSG was done 3 months later to verify occlusion of the fallopian tubes. Results: 26 of 30 patients (86%) had bilateral tubal occlusion as determined by HSG. There were minor side effects such as: pain (66.7%), yellow discharge (100%) and menstrual abnormalities (13.3%). One woman became pregnant after HSG showed bilateral occlusion. HSG may interfere with the action of the quinacrine. Conclusion: QS is a simple and safe alternative to surgical sterilization with few side effects.