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Myocardial hypertrophy of the recipient twins in twin‐to‐twin transfusion syndrome and cerebral palsy
Author(s) -
Hyodo H.M.,
Unno N.,
Masuda H.,
Watanabe T.,
Kozuma S.,
Taketani Y.
Publication year - 2003
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/s0020-7292(02)00252-7
Subject(s) - medicine , monochorionic twins , myocardial hypertrophy , cerebral palsy , pathogenesis , cardiology , incidence (geometry) , muscle hypertrophy , twin to twin transfusion syndrome , pediatrics , pregnancy , fetus , physical medicine and rehabilitation , genetics , physics , optics , biology
Objectives: This study was performed to determine risk factors for cerebral palsy (CP) in monochorionic twins, especially with twin‐to‐twin transfusion syndrome (TTTS). Methods: In 33 pathologically confirmed monochorionic pregnancies, we analyzed the incidence of cardiovascular and neurological complications. Results: Seventeen cases were diagnosed as TTTS. Myocardial hypertrophy was detected in seven recipient twins of TTTS, but not found in the donor twins of TTTS or in non‐TTTS. CP developed in six out of 29 in TTTS and one out of 32 in non‐TTTS. In TTTS, all the cases with CP were seen in the recipient twins. The development of CP was significantly associated with cardiovascular complications such as myocardial hypertrophy and hydropic changes. Conclusions: Myocardial hypertrophy found in the recipient twins in TTTS seems to be a risk for developing CP later on, which may have implications in understanding the pathogenesis of CP.