Premium
Cutaneous metastasis of gestational choriocarcinoma
Author(s) -
Chama C.M.,
Nggada H.A.,
Nuhu A.
Publication year - 2002
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/s0020-7292(01)00589-6
Subject(s) - medicine , choriocarcinoma , vaginal bleeding , methotrexate , endometrium , pregnancy test , gestation , uterus , pregnancy , metastasis , lesion , cyclophosphamide , biopsy , radiology , gestational trophoblastic disease , gestational sac , urinary system , gynecology , pathology , chemotherapy , cancer , biology , genetics
A 40‐year‐old woman presented with subcutaneous masses on her chest wall, abnormal vaginal bleeding and an enlarged uterus. Chest X‐ray and liver ultrasound revealed metastatic disease to these sites, respectively. A urine human chorionic gonadotrophin assay was positive. A biopsy of the chest wall lesion and endometrium revealed choriocarcinoma. Treatment with methotrexate, actinomycin‐D and cyclophosphamide led to complete resolution of the disease on examination, X‐ray and ultrasound scans. The urinary pregnancy test became negative.