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Prognostic factors related to cervical cancer survival in Mexican women
Author(s) -
FloresLuna L,
SalazarMartinez E,
EscuderoDe los Rios P,
GonzalezLira G,
ZamoraMuñoz S,
LazcanoPonce E
Publication year - 2001
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/s0020-7292(01)00471-4
Subject(s) - medicine , cervical cancer , oncology , gynecology , cancer , demography , obstetrics , sociology
Objective : To identify prognostic survival factors among Mexican women with cervical cancer. Methods : A total of 378 women with cervical cancer admitted from 1984 to 1996 to our referral hospital were evaluated, using survival analysis (Kaplan–Meier and Cox proportional hazards method). We designed a symptom index which included asymptomatic conditions, severity of symptoms and comorbidity. Results : Overall 5‐year survival was 66.6%. The shortest survival time was for FIGO stage IV (21.5%, P <0.001) and adenosquamous histologic type (53.1%, P =0.15). The main prognostic factors were primary symptoms (RR, 2.6; 95% CI, 1.02–6.66); systemic symptoms (RR, 3.3; 95% CI, 1.23–9.01); FIGO stage IV (RR, 5.5; 95% CI, 2.36–12.96); and oncogenic symptoms (prognostic comorbidity present) (RR, 2.3; 95% CI, 1.08–4.89). Conclusions : Our findings show that clinical stage and several types of symptoms influence CC survival. This present strategy to assess morphological and clinical characteristics may be a more accurate indicator of survival rate and potentially an efficient indicator of new therapeutic alternatives.