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Acute fatty liver of pregnancy
Author(s) -
VigilDe Gracia P.,
Lavergne J.A.
Publication year - 2001
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/s0020-7292(00)00370-2
Subject(s) - vigil , medicine , gynecology , library science , philosophy , theology , computer science
Ž . Acute fatty liver of pregnancy AFLP was distinguished as a specific clinical entity unique to pregnancy in 1940 by Sheehan. AFLP is a rare disease, the incidence is estimated to be one case w x per 6692 to 13 328 deliveries 1,2 . Pathological changes as a rule improve rapidly after delivery. Liver biopsy is the best way to confirm the diagnosis, but because it is invasive, it is not always performed. Furthermore, today we can take advantage of non-invasive procedures to demonstrate fat in the liver and to exclude other liver diseases such as viral hepatitis. The objective of this study was to report our experience with the diagnostic, the clinical and biochemical findings, complications and the maternal-perinatal outcome in 10 consecutive cases of AFLP. The ‘Complejo Hospitalario Metropolitano de la Caja de Seguro Social’ in Panama City, serves as a hospital of tertiary care facility and reference