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Risk factors for meconium aspiration syndrome in infants born through thick meconium
Author(s) -
Meydanli M.M.,
Dilbaz B.,
Çalişkan E.,
Dilbaz S.,
Haberal A.
Publication year - 2001
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/s0020-7292(00)00265-4
Subject(s) - medicine , meconium , meconium aspiration syndrome , obstetrics , odds ratio , relative risk , amniotic fluid , apgar score , gestational age , risk factor , gestation , pregnancy , gynecology , fetus , confidence interval , genetics , biology
Objective : To determine risk factors for meconium aspiration syndrome (MAS). Method : A cohort study was conducted of 70 consecutive singleton pregnancies complicated with thick meconium‐stained amniotic fluid delivered at ≥37 weeks’ gestation. Cases were randomized either for elective abdominal delivery or spontaneous vaginal delivery after 20 min of external fetal heart rate (FHR) monitoring. Risk estimation analysis for MAS was performed calculating relative risks (RR) and odds ratios (OR). Results : The presence of meconium below the vocal cords (RR=7.3, 95% CI=2.6–20.3), non‐reassuring FHR tracings (RR=3.0, 95% CI=1.2–7.5), Apgar score ≤6 at 5 min (RR=3.8, 95% CI=1.7–8.4) and an umbilical cord plasma erythropoietin (UCPer) level >50 mlU/ml (RR=5.0, 95% CI=2.1–12.0) were found to be significant risk factors for MAS. The presence of meconium below the vocal cords (OR=33.4, 95% CI=3.6–303.7) and non‐reassuring FHR tracings (OR=12.2, 95% CI=1.3–111.7) remained as significant risk factors at the end of the multivariate analysis. Conclusion : Non‐reassuring FHR tracings and the presence of meconium below vocal cords are associated with an increased risk for MAS in infants born through thick meconium.